Isotopically Labeled Compounds
Medchemexpress LLC Tristearin-d5 | 55256-03-6 | 98.9% | 50 MG
Tristearin-d5 is a deuterium labeled triglyceride derived from three units of stearic acid. It is intended for research use only, not for patient use. Stable heavy isotopes, such as deuterium in Tristearin-d5, are often incorporated into drug molecules for use as tracers during the drug development process, with the potential to influence pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Ivacaftor-d18 (synonyms: VX-770-d18) | 1413431-05-6 | 92.9% | 1 MG
Ivacaftor-d18 is the deuterium labeled Ivacaftor. It is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively. It is intended for research use only.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Molecular weight: 410.60
- Formula: C24H10D18N2O3
- Appearance: solid
- Color: white to off-white
- Unlabeled CAS: 873054-44-5
Medchemexpress LLC 7-keto-Deoxycholic acid | 911-40-0 | 99.71% | 406.56 | 25 MG
7-keto-Deoxycholic acid is a metabolite of bile acids found in *Clostridium absonum*. It can also be converted from *Lactobacillus* and *Bifidobacterium* under specific conditions. It exhibits an increased bioconversion rate when an equimolar concentration of deoxycholic acid is added.
- Induced by deoxycholic acid and subsequently metabolized
- *E. lentum-like c-25* converts cholic acid to deoxycholic acid and 7-keto-Deoxycholic acid under anaerobic incubation
Medchemexpress LLC Nifedipine-d6 | 1188266-14-9 | >98% | 5 MG
Nifedipine-d6 (BAY-a-1040-d6) is deuterium labeled nifedipine, which is a potent calcium channel blocker. It is intended for research use only.
- Deuterium labeled nifedipine
- Potent calcium channel blocker
- Intended for research use only
Medchemexpress LLC Bezafibrate-d6 | 1219802-74-0 | 98.9% | 1 MG
Bezafibrate-d6 is the deuterium labeled Bezafibrate. Bezafibrate is an agonist of PPAR, with EC50s of 50 μM, 60 μM, and 20 μM for human PPARα, PPARγ, and PPARδ respectively, and 90 μM, 55 μM, and 110 μM for murine PPARα, PPARγ, and PPARδ respectively. It is used as a hypolipidemic agent.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Fleroxacin-d3 hydrochloride | 79660-72-3 | 98.8% | 1 MG
Fleroxacin-d3 (hydrochloride) is the deuterium labeled Fleroxacin (hydrochloride). It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer for various analyses.
- Functions as an internal standard for quantitative analysis.
- Useful for NMR, GC-MS, or LC-MS applications.
- Deuteration can impact pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Tizoxanide-d4 | 1246817-56-0 | 99.8% | 1 MG
Tizoxanide-d4 is the deuterium labeled form of Tizoxanide, which is the active metabolite of Nitazoxanide. This thiazolide anti-infective compound is effective against anaerobic bacteria, protozoa, and various viruses, including anti-HIV-1 activities. It is intended for research use only and can be used as a tracer or an internal standard for quantitative analysis.
- Deuterium labeled compound
- Active metabolite of Nitazoxanide
- Effective against anaerobic bacteria, protozoa, and various viruses
- Can be used as a tracer or internal standard
- Useful for quantitative analysis by methods like NMR, GC-MS, or LC-MS
Medchemexpress LLC Glyburide-d3 (deuterium-labeled glibenclamide) | 1219803-02-7 | MFCD06658648 | 99.6% | 497.02 | C23H25D3ClN3O5S | 10 MG
Glyburide-d3 is the deuterium-labeled isotopologue of glibenclamide supplied as a solid research reagent and analytical standard. It serves as a labeled internal standard and is used in studies of ATP-sensitive K+ (KATP) channel activity and related analytical workflows.
- Deuterium-labeled internal standard for analytical assays.
- High purity: 99.64%.
- CAS number: 1219803-02-7.
- Molecular weight: 497.02; chemical formula: C23H25D3ClN3O5S.
- Appearance: white to off-white solid.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Solubility: DMSO 100 mg/mL; H2O 0.1 mg/mL (ultrasonic/warming recommended).
Medchemexpress LLC Ipratropium-d3 bromide | 22254-24-6 | 98.0% | 5 MG
Ipratropium-d3 bromide is the deuterium labeled Ipratropium bromide. It is a muscarinic receptor antagonist, with binding IC50 values of 2.9 nM, 2 nM, and 1.7 nM for M1, M2, and M3 receptors, respectively. It can be used in the research for COPD (chronic obstructive pulmonary disease) and asthma, and serves as a tracer or an internal standard for quantitative analysis.
- Deuterium labeled compound
- Acts as a muscarinic receptor antagonist
- Suitable for research on COPD and asthma
- Functions as a tracer
- Useful as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Imidacloprid-d4 | 1015855-75-0 | 98.9% | 5 MG
Imidacloprid-d4 is the deuterium labeled version of Imidacloprid. Imidacloprid is recognized as an effective and broadly used neonicotinoid pesticide, employed for controlling pests that affect cereals, vegetables, tea, and cotton. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Application as a tracer.
- Internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.
Medchemexpress LLC Imidacloprid-d4 | 1015855-75-0 | 98.9% | 1 MG
Imidacloprid-d4 is a deuterium-labeled form of Imidacloprid, a neonicotinoid pesticide used to control pests in various crops. This compound is intended for research use only. Stable heavy isotopes, like deuterium, are incorporated into drug molecules for use as tracers in drug development, with potential effects on pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Tristearin-d5 | 55256-03-6 | 98.9% | 10 MG
Tristearin-d5 is the deuterium labeled Tristearin, a triglyceride derived from three units of stearic acid. Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation during the drug development process. Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Benzyl alcohol-d1 (Benzenemethanol-d1) | 14915-25-4 | 95.7% | 50 MG
Benzyl alcohol-d1, also known as Benzenemethanol-d1, is a deuterium-labeled analog of Benzyl alcohol, intended for research use only.
- Molecular weight of 109.14 and chemical formula of C7H7DO
- Appears as a colorless to light yellow liquid
- Incorporates stable heavy isotopes of hydrogen (deuterium)
- Soluble in DMSO (≥ 175 mg/mL), Ethanol (≥ 100 mg/mL), and water (20 mg/mL with ultrasonication)
- Serves as a tracer in scientific investigations
- Employed as an internal standard for quantitative analysis in techniques such as NMR, GC-MS, and LC-MS